Spis is one of the most beautiful and distinctive of Slovak regions. Thanks to its magnificent scenery and an abundance of cultural and historical sights it is also one of the most attractive for tourists. It is bordered to the west by the High Tatras and the Belanske Tatras, to the south by the Low Tatras and the Slovenské Rudohorie (Slovak Ore Mountains), and to the north by Spisska Magura.

Spis county came into being in the middle of the 12th century a the time of King Gejza and of the German colonisation which influenced Spis's entire history. Spis was traversed by important trade routes secured by castles, the most important being the Spis Castle, the largest medieval fortress in Slovakia and one of the most extensive in central Europe. Together with Spisske Podhradie and Spisska Kapitula it forms an architectural entity recognised in UNESCO's World Heritage Registry.

Also well worth a visit is the 13th-century Early Gothic church in the nearby community of Zehra, which boasts an attractive profile and, particularly, an abudance of esteemed wall paintings. Many Spis towns are remarkable for their architecture. These include Levoca, with its Gothic St.James's Church containing the tallest Gothic wooden altar in the world by Master Pavol, Spisska Nova Ves, the central town of Spis, and Stara Lubovna, one of the oldest towns in Spis region

Drevenik is the largest travertine area in Slovakia.

In Spiska Bela town you can visit Petzval Museum.